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BioMed Research International
Volume 2013 (2013), Article ID 685196, 4 pages
Research Article

Toxocara Seroprevalence in Patients with Idiopathic Parkinson's Disease: Chance Association or Coincidence?

1School of Health, Adiyaman University, 02040 Adiyaman, Turkey
2Department of Neurology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey
3Department of Neurology, Faculty of Medicine, Firat University, 23119 Elazig, Turkey
4Department of Biostatistics, Faculty of Medicine, Ankara University, 06100 Ankara, Turkey

Received 10 April 2012; Accepted 23 July 2012

Academic Editor: Luis I. Terrazas

Copyright © 2013 Tuncay Çelik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Most cases of idiopathic Parkinson disease (IPD) are believed to be due to a combination of genetic and environmental factors. The purpose of this study is to investigate the relationship between toxocariasis and Parkinson disease (PD). Patients were selected from people who were admitted to the Movement Disorders Branch, Neurology Department of Elazığ University Faculty of Medicine Elazığ, Turkey. We studied specific IgG antibodies against Toxocara canis (T. canis) in 50 patients with idiopathic Parkinson and 50 healthy volunteers. We investigated the clinical history of three patients infected with T. canis. We also studied specific IgG antibodies against Toxoplasma gondii in these groups. Antibodies anti-Toxocara canis were found in 3 idiopathic PD (6%) ( ) and antibody titer was not found in control. A patient had history of the presence of dog in current dog ownership. We did not detect any statistically significant association between T. canis and IPD. But, we believe that further comprehensive studies are required for understanding whether there is a causal relation between toxocariasis and PD. We didn’t find possible association between Toxoplasma gondii and IPD ( ).