Microenvironment and Radiation Therapy

Table 1

Antiangiogenic agents with radiosensitizing potentials.

Category	Representative strategies/protein/drugs	References
Endogenous angiogenesis inhibitor	Angiostatin,	[45–47]
	Endostatin	[48–50]
Anti-VEGF antibody	Bevacizumab	[36, 40, 52–54]
Anti-VEGFR antibody	DC101	[43, 55]
Anti-VEGFR tyrosine kinase inhibitor and multitarget tyrosine kinase inhibitor	Vatalanib (PTK787),	[56, 57]
	Vandetanib (ZD6474),	[58, 59]
	Cediranib (AZD2171)	[60, 61]
	Semaxanib (SU5416),	[62, 63]
	SU6668	[64]
	SU11657	[44]
	Sunitinib (SU11248)	[65, 66]
Others	TNP-470	[51, 67, 68]
	Thalidomide	[69]