Recombinant Rat CC10 Protein Inhibits PDGF-Induced Airway Smooth Muscle Cells Proliferation and Migration

Figure 4

Effects of recombinant rat CC10 protein on PDGF-BB-induced ASMCs viability/proliferation. (a) Comparison of the effect of CC10 protein on ASMCs viability to that of HC by WST-1 assay. (b) Comparison of the effect of CC10 protein on ASMCs proliferation with that of HC by Roche RTCA DP assay. Data was generated from ASMCs with 4 replicates. Percentage of viability was obtained by comparing OD values to that of ASMCs in a control group treated in parallel with PBS. ASMCs proliferation variation was obtained by calculating the changes of ASMCs to baseline. Data was shown as means ± SD values. **𝑃<0.01 PDGF group versus control, *𝑃<0.05 PDGF group versus control, ^##𝑃<0.01 CC10 group versus PDGF group, ^††𝑃<0.01 HC group versus PDGF group, and ^†𝑃<0.05 HC group versus PDGF group.

(a)

(b)