Review Article

HLA-G/C, miRNAs, and Their Role in HIV Infection and Replication

Figure 4

The 263del/ins SNP associates strongly with surface expression of HLA-C. (a) 263del disrupts the binding site of miR-148a not altering the expression of HLA-C. (b) 263insG increases the stability of the binding with the miR-148a reducing surface expression of HLA-C and the recognition by CTL.
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