N-Acetylcysteine Prevents Hypertension via Regulation of the ADMA-DDAH Pathway in Young Spontaneously Hypertensive Rats
Figure 3
Protein levels of NOS enzymes in SHR and control WKY rats. Representative western blots (a) showed DDAH-1 (34 kDa), DDAH-2 (30 kDa), eNOS (150 kDa), nNOS-α (160 kDa), and nNOS-β (140 kDa) bands in WKY rats and SHR at 12 weeks of age. Relative abundance of renal cortical (b) DDAH-1, (c) DDAH-2, (d) eNOS, (e) nNOS-α, and (f) nNOS-β as quantified. SHR + NAC, spontaneously hypertensive rat treated with N-acetylcysteine; /group; SHR versus WKY; SHR + NAC versus SHR.
