Figure 3: Kinetics of antibody production during T. canis infection by STAT6−/− and STAT6+/+ mice. (a) Anti-T. canis specific IgG2a. (b) Anti-T. canis specific IgG1 and (c) Total IgE. Sera were taken from the vein tail of each mouse at time points described. ELISA plates were sensitized with 1  g/well of soluble extract of T. canis. The graphs show the mean SE ( animals) and are representative of two independent experiments. comparing STAT6−/− versus STAT6+/+ at the same time point.