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BioMed Research International
Volume 2013 (2013), Article ID 698141, 14 pages
Research Article

Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films

1Department of Chemistry and CICECO, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal
2Department of Cellular Biology and Histology, Faculty of Medicine and Odontology, University of the Basque Country (UPV/EHU), Barrio Sarriena s/n, 48940 Leioa, Spain
3“Materials + Technologies” Group, Department of Chemical and Environmental Engineering, Polytechnic School, University of the Basque Country (UPV/EHU), Plaza Europa 1, 20018 San Sebastián, Spain

Received 30 April 2013; Accepted 15 July 2013

Academic Editor: Dong-Wook Han

Copyright © 2013 Andrea G. P. R. Figueiredo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as cross-linker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.