HLA-B*40 Allele Plays a Role in the Development of Acute Leukemia in Mexican Population: A Case-Control Study

Table 2

Gene frequencies of HLA-B alleles in patients with ALL compared with umbilical cord blood samples, as a control group.

B* allele	Patients 𝑁=213		Controls 𝑁=731		P	OR	95% CI
	𝑛	g. f.	𝑛	g. f.
07	16	0.0375	60	0.0410	NS
08	10	0.0234	40	0.0273	NS
13	4	0.0093	14	0.0095	NS
14	15	0.0352	55	0.0376	NS
15	35	0.0821	135	0.0923	NS
18	11	0.0258	42	0.0287	NS
27	8	0.0187	19	0.0129	NS
35	73	0.1713	296	0.2024	NS
38	10	0.0234	15	0.0102	NS
39	52	0.1220	254	0.1737	0.004	0.61	0.42–0.87
40	62	0.1455	144	0.0984	0.003	1.67	1.16–2.40
41	9	0.0211	13	0.0088	NS
42	1	0.0023	9	0.0061	NS
44	25	0.0586	75	0.0512	NS
45	10	0.0234	18	0.0123	NS
48	15	0.0352	57	0.0389	NS
49	13	0.0305	29	0.0198	NS
51	23	0.0539	86	0.0588	NS
52	13	0.0305	40	0.0273	NS
53	5	0.0117	17	0.0116	NS
55	3	0.0070	2	0.0013	NS
56	1	0.0023	2	0.0013	NS
57	3	0.0070	15	0.0102	NS
58	4	0.0093	6	0.0041	NS

ALL: acute lymphoid leukemia; g. f.: gene frequency; OR: odds ratio; CI: confidence interval; NS: not significant.