Distal Airway Impairment in Obese Normoreactive Women
Table 2
Lung function data of the BMI-normal, overweight, and obese patients, in the AHR+ population.
Variables
Total
BMI < 25
25 ≤ BMI < 30
BMI ≥ 30
value
Smoking
0.3120
Yes
18 (14.63)
13 (18.31)
4 (20.00)
1 (3.13)
No
93 (75.61)
51 (71.83)
14 (70.00)
28 (87.50)
Former smoker
12 (9.76)
7 (9.86)
2 (10.00)
3 (9.38)
Age (years)
41.50 (12.94)
37.98 (13.28)
45.57 (13.03)
46.80 (9.44)
0.0025
BMI (kg/m2)
25.19 (6.26)
20.66 (2.05)
27.58 (1.45)***
33.77 (4.11)***
<0.0001
FVC (L)
3.04 (0.52)
3.18 (0.45)
2.98 (0.60)
2.78 (0.54)
0.0004
FVC (% pred)
0.95 (0.13)
0.96 (0.12)
0.94 (0.11)
0.94 (0.14)
0.5261
FEV1 (L)
2.57 (0.50)
2.73 (0.47)
2.44 (0.47)**
2.31 (0.46)***
<0.0001
FEV1 (% pred)
0.93 (0.14)
0.96 (0.13)
0.90 (0.11)
0.92 (0.15)
0.1930
FEV1/FVC (%)
0.84 (0.07)
0.86 (0.04)
0.82 (0.05)
0.83 (0.05)
0.1068
FVC fall (%)
17.52 (8.42)
16.76 (9.60)
19.02 (5.15)
18.26 (7.21)
0.3434
FEV1 fall (%)
24.97 (8.15)
25.38 (9.58)
24.71 (5.29)
24.26 (6.10)
0.7683
FEV1 DRS
0.09 (0.20)
0.10 (0.22)
0.07 (0.08)
0.11 (0.18)
0.6897
FVC DRS
0.06 (0.15)
0.06 (0.18)
0.05 (0.05)
0.08 (0.13)
0.5523
CI
0.69 (0.26)
0.65 (0.25)
0.77 (0.15)
0.76 (0.24)
0.0591
Data are presented as median (interquartile range) (all but smoking) and (%) (smoking). BMI: body mass index; FEV1: forced expiratory volume in one second; FVC: forced volume capacity; DRS: dose-response slope; CI: closing index.
*
versus BMI < 25; ** versus BMI < 25; *** versus BMI < 25.
