Distal Airway Impairment in Obese Normoreactive Women
Table 3
Lung function data of the BMI-normal, overweight, and obese patients, in the AHR− population.
Variables
Total
BMI < 25
25 ≤ BMI < 30
BMI ≥ 30
value
Smoking
0.2350
Yes
21 (12.35)
16 (14.41)
4 (9.52)
1 (5.88)
No
135 (79.41)
86 (77.48)
36 (85.71)
13 (76.47)
Former smoker
14 (8.24)
9 (8.11)
2 (4.76)
3 (17.64)
Age (years)
40.70 (12.71)
37.86 (12.48)
45.29 (12.22)**
47.90 (9.32)***
0.0003
BMI (kg/m2)
24.25 (4.67)
21.57 (2.21)
27.39 (1.54)***
33.92 (3.98)***
<0.0001
FVC (L)
3.31 (0.62)
3.47 (0.57)
2.98 (0.62)***
3.10 (0.54)**
<0.0001
FVC (% pred)
1.02 (0.14)
1.03 (0.14)
0.98 (0.14)*
1.06 (0.13)
0.0415
FEV1 (L)
2.82 (0.55)
2.97 (0.53)
2.51 (0.50)***
2.63 (0.47)**
<0.0001
FEV1 (% pred)
1.01 (0.14)
1.02 (0.14)
0.96 (0.14)*
1.06 (0.14)
0.0226
FEV1/FVC (%)
0.85 (0.06)
0.85 (0.06)
0.84 (0.05)
0.85 (0.04)
0.5918
FVC fall (%)
6.87 (5.68)
6.81 (5.61)
6.95 (6.05)
7.05 (5.54)
0.9337
FEV1 fall (%)
11.14 (6.54)
11.26 (6.40)
10.62 (7.25)
11.58 (5.89)
0.6511
FEV1 DRS
0.006 (0.003)
0.006 (0.003)
0.005 (0.003)
0.006 (0.002)
0.4671
FVC DRS
0.003 (0.003)
0.004 (0.003)
0.003 (0.002)
0.005 (0.002)
0.7422
CI
0.67 (0.72)
0.68 (0.79)
0.70 (0.63)
0.72 (0.30)
0.5918
Data are presented as median (interquartile range) (all but smoking) and (%) (smoking). BMI: body mass index; FEV1: forced expiratory volume in one second; FVC: forced volume capacity; DRS: dose-response slope; CI: closing index.
*
versus BMI < 25; ** versus BMI < 25; *** versus BMI < 25.
