Distal Airway Impairment in Obese Normoreactive Women
Table 5
Analyses of covariance for the impact of BMI on the relationship between FVC DRS (independent variable) and FEV1 DRS (predicted variable), adjusted for age and baseline respiratory values.
Parameter
Entire population
AHR+
AHR−
Estimate
Std. error
value
Estimate
Std. error
value
Estimate
Std. error
value
(Intercept)
0.02
0.19
0.91
0.00
0.20
0.99
0.52
0.01
Age
0.00
0.11
0.00
0.00
0.98
0.01
0.23
Baseline FVC
0.18
0.46
0.19
0.24
0.44
0.23
0.40
Baseline FEV1
0.06
0.21
0.77
0.02
0.29
0.94
0.10
0.28
0.73
Log(FVC DRS)
0.91
0.04
<2e −16
0.86
0.05
<2e −16
0.62
0.09
<2e −16
BMI (overweight)
0.35
0.87
0.42
0.44
0.34
0.93
0.94
0.33
BMI (obese)
0.30
0.06
0.11
0.33
0.74
1.06
0.12
Log(FVC DRS) * BMI (overweight)
0.00
0.07
0.96
0.18
0.12
0.15
0.17
0.16
0.30
Log(FVC DRS) * BMI (obese)
0.06
0.01
0.08
0.09
0.41
0.17
0.03
FEV1: forced expiratory volume in one second; FVC: forced volume capacity; DRS: dose-response slope. BMI-normal subjects were considered as the control group.
