Research Article

Improved scFv Anti-HIV-1 p17 Binding Affinity Guided from the Theoretical Calculation of Pairwise Decomposition Energies and Computational Alanine Scanning

Figure 5

Docking structural comparison of wild type (1) and mutant form (M100G, 2) of scFv anti-p17 against five peptides: (a) p17.1, (b) p17.3, (c) p17.7, (d) p17.8, and (e) p17.9, respectively. A stick representation of side chains of scFv predicted to interact through hydrogen bond to peptides (scaled ball and stick). Hydrogen bonds are presented as dashed lines.
713585.fig.005a
(a)
713585.fig.005b
(b)