Altered mRNA Expression Related to the Apoptotic Effect of Three Xanthones on Human Melanoma SK-MEL-28 Cell Line

Figure 3

Mitochondrial cytochrome C was examined using flow cytometry after 48 h treatment with α-mangostin, γ-mangostin, and 8-deoxygartanin. Data were obtained from 20,000 events and presented as the percentage of mitochondrial cytochrome C compared to the untreated control. The values are shown as the mean ± SEM of three independent experiments. Treatments significantly different from the untreated control at 𝑃<0.05 are presented as * and 𝑃<0.01 as **.