Formulation Development and Stability Studies of Norfloxacin Extended-Release Matrix Tablets

Table 1

Composition of tablets containing hydroxypropylmethyl cellulose (HPMC) or poly(ethylene oxide) (PEO).

Composition	For one tablet	For one tablet
Norfloxacin	700 mg	700 mg
Polymer	20%	30%
HPMC K100LV
HPMC K4M
PEO N60K
PEO WSR 301
Magnesium stearate	1%	1%
Colloidal silicon dioxide	0.5%	0.5%
Microcrystalline cellulose	q.s.	q.s.
Total weight	1.07 g	1.07 g