Alantolactone Induces Apoptosis in HepG2 Cells through GSH Depletion, Inhibition of STAT3 Activation, and Mitochondrial Dysfunction

<table>Effect of alantolactone on the expressions of apoptosis regulators. HepG2 cells were treated with or without 40 <i>μ</i>M alantolactone for 6 and 12 h. The expression of Phospho-STAT3, Bax, Bcl-2, and caspase-3 was measured by Western blot analysis.</table>

BioMed Research International

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Figure 8

Figure 8: Alantolactone Induces Apoptosis in HepG2 Cells through GSH Depletion, Inhibition of STAT3 Activation, and Mitochondrial Dysfunction 