BioMed Research International / 2013 / Article / Fig 4

Research Article

CD59 Underlines the Antiatherosclerotic Effects of C-Phycocyanin on Mice

Figure 4

Determination of cell apoptosis in different groups. (a) Photos of TUNEL method ( ). The nuclei of apoptotic cells were dyed brownish yellow. The intima of the aorta in a high-fat-diet control group had brownish-yellow granules. The color was darker in control group than that in C-PC treatment group and CD59 transfection group. However, brownish-yellow granules were the least and the color was the lightest in C-PC+CD59 synergy group. (A) Control group, (B) C-PC treatment group, (C) CD59 transfection group, and (D) C-PC+CD59 synergy group. (b) Comparison of apoptosis rates. Compared with control group, the numbers of apoptotic cells decreased and the apoptosis rates were gradually reduced in single C-PC or CD59 treated group, and the differences were significant (* ). But the apoptosis rates were further lowered when the mice were treated with CD59 and C-PC at the same time (** ).

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