BioMed Research International / 2013 / Article / Fig 9

Research Article

CD59 Underlines the Antiatherosclerotic Effects of C-Phycocyanin on Mice

Figure 9

Determination of MMP-2 protein levels. (a) Photos of immunohistochemistry ( ). The membrane and cytoplasm of positive cells showed a brownish-yellow dye after immunohistochemistry. In high-fat-fed control group, plenty of apparent brownish-yellow particles were observed in cells of atherosclerotic plaque and granules were denser than those in other groups. There was no obvious plaque and the stain of endothelial cells in C-PC treatment group and CD59 transfection group was lighter than that of control group. In C-PC+CD59 synergy group, there were no apparent positive cells. (A) Control group, (B) C-PC treatment group, (C) CD59 transfection group, and (D) C-PC+CD59 synergy group. (b) The IOD of MMP-2 protiens. IOD values represent the levels of protein expression. Compared with the control group, the IOD values in CD59 or C-PC treated groups were decreased and the differences were significant (* ). The IOD values were further enhanced in C-PC and CD59 synergy group.

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