Figure 2: Predicted folding of selected single-stranded DNA aptamers. Stem-loop structures of aptamers play a fundamental role in target molecule binding. Respective consensus sequences of aptamers binding to (a) Hepatitis C virus (HCV) E2 glycoprotein on the cell surface [24] and (b) S. Typhimurium outer membrane proteins (OMPs) [25] were analyzed using the MFold programme [26] for secondary structure predictions.