Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2013, Article ID 736438, 9 pages
http://dx.doi.org/10.1155/2013/736438
Research Article

Expression Analysis of SPARC/Osteonectin in Oral Squamous Cell Carcinoma Patients: From Saliva to Surgical Specimen

1Pathology Unit, Istituto Nazionale Tumori “Fondazione Pascale”-IRCCS, Napoli, Italy
2Head and Neck Medical Oncology Unit, Istituto Nazionale Tumori “Fondazione Pascale”-IRCCS, Napoli, Italy
3Department of Surgical Sciences, Section of Anatomic Pathology, Second Section of Oral Pathology, University of Foggia, Foggia, Italy

Received 11 July 2013; Accepted 1 November 2013

Academic Editor: Franco M. Buonaguro

Copyright © 2013 Gabriella Aquino et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. D. R. Thompson, Head and Neck Pathology, 2006.
  2. P. Lohavanichbutr, J. Houck, D. R. Doody et al., “Gene expression in uninvolved oral mucosa of OSCC patients facilitates identification of markers predictive of OSCC outcomes,” PLoS ONE, vol. 7, no. 9, Article ID e46575, 2012. View at Publisher · View at Google Scholar
  3. C. Chen, E. Méndez, J. Houck et al., “Gene expression profiling identifies genes predictive of oral squamous cell carcinoma,” Cancer Epidemiology Biomarkers and Prevention, vol. 17, no. 8, pp. 2152–2162, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. P. Choi, C. D. Jordan, E. Mendez et al., “Examination of oral cancer biomarkers by tissue microarray analysis,” Head and Neck Surgery, vol. 134, no. 5, pp. 539–546, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. P. Bornstein and E. H. Sage, “Matricellular proteins: extracellular modulators of cell function,” Current Opinion in Cell Biology, vol. 14, no. 5, pp. 608–616, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. R. A. Brekken and E. H. Sage, “SPARC, a matricellular protein: at the crossroads of cell-matrix communication,” Matrix Biology, vol. 19, no. 8, pp. 816–827, 2001. View at Google Scholar · View at Scopus
  7. A. Bellahcene and V. Castronovo, “Increased expression of osteonectin and osteopontin, two bone matrix proteins, in human breast cancer,” American Journal of Pathology, vol. 146, no. 1, pp. 95–100, 1995. View at Google Scholar · View at Scopus
  8. C. Jones, A. Mackay, A. Grigoriadis et al., “Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer,” Cancer Research, vol. 64, no. 9, pp. 3037–3045, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. C. A. DeRosa, B. Furusato, S. Shaheduzzaman et al., “Elevated osteonectin/SPARC expression in primary prostate cancer predicts metastatic progression,” Prostate Cancer and Prostatic Diseases, vol. 15, pp. 150–156, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. E. Yang, J. K. Hyun, H. K. Kwi, H. Rhee, K. K. Nam, and H. Kim, “Frequent inactivation of SPARC by promoter hypermethylation in colon cancers,” International Journal of Cancer, vol. 121, no. 3, pp. 567–575, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Chlenski, S. Liu, S. E. Crawford et al., “SPARC is a key Schwannian-derived inhibitor controlling neuroblastoma tumor angiogenesis,” Cancer Research, vol. 62, no. 24, pp. 7357–7363, 2002. View at Google Scholar · View at Scopus
  12. S. A. Rempel, W. A. Golembieski, J. L. Fisher, M. Maile, and A. Nakeff, “SPARC modulates cell growth, attachment and migration of U87 glioma cells on brain extracellular matrix proteins,” Journal of Neuro-Oncology, vol. 53, no. 2, pp. 149–160, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. P. A. Puolakkainen, R. A. Brekken, S. Muneer, and E. H. Sage, “Enhanced growth of pancreatic tumors in SPARC-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis,” Molecular Cancer Research, vol. 2, no. 4, pp. 215–224, 2004. View at Google Scholar · View at Scopus
  14. N. Sato, N. Fukushima, N. Maehara et al., “SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions,” Oncogene, vol. 22, no. 32, pp. 5021–5030, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Said, H. F. Frierson, M. Sanchez-Carbayo, R. A. Brekken, and D. Theodorescu, “Loss of SPARC in bladder cancer enhances carcinogenesis and progression,” Journal of Clinical Investigation, vol. 123, pp. 751–766, 2013. View at Google Scholar
  16. J. F. DiMartino, N. J. Lacayo, M. Varadi et al., “Low or absent SPARC expression in acute myeloid leukemia with MLL rearrangements is associated with sensitivity to growth inhibition by exogenous SPARC protein,” Leukemia, vol. 20, no. 3, pp. 426–432, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. I. W. Dimery and W. K. Hong, “Overview of combined modality therapies for head and neck cancer,” Journal of the National Cancer Institute, vol. 85, no. 2, pp. 95–111, 1993. View at Google Scholar · View at Scopus
  18. B. Lallemant, A. Evrard, C. Combescure et al., “Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse,” BMC Cancer, vol. 9, article 370, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Pérez-Sayáns, M. D. Reboiras-López, P. Gayoso-Diz et al., “Non-computer-assisted liquid-based cytology for diagnosis of oral squamous cell carcinoma,” Biotechnic and Histochemistry, vol. 87, pp. 59–65, 2012. View at Google Scholar
  20. P. Choi, C. D. Jordan, E. Mendez et al., “Examination of oral cancer biomarkers by tissue microarray analysis,” Head and Neck Surgery, vol. 134, no. 5, pp. 539–546, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. P. Choi and C. Chen, “Genetic expression profiles and biologic pathway alterations in head and neck squamous cell carcinoma,” Cancer, vol. 104, pp. 1113–1128, 2005. View at Google Scholar
  22. S.-Y. Liu, C.-L. Lu, C.-T. Chiou et al., “Surgical outcomes and prognostic factors of oral cancer associated with betel quid chewing and tobacco smoking in Taiwan,” Oral Oncology, vol. 46, no. 4, pp. 276–282, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. A. G. Zygogianni, G. Kyrgias, P. Karakitsos et al., “Oral squamous cell cancer: early detection and the role of alcohol and smoking,” Head and Neck Oncology, vol. 3, no. 1, article 2, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. K. Koo, R. Barrowman, M. McCullough, T. Iseli, and D. Wiesenfeld, “Non-smoking non-drinking elderly females: a clinically distinct subgroup of oral squamous cell carcinoma patients,” International Journal of Oral and Maxillofacial Surgery, vol. 42, pp. 929–933, 2013. View at Google Scholar
  25. G. S. Wong and A. K. Rustgi, “Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis,” British Journal of Cancer, vol. 108, pp. 755–761, 2013. View at Google Scholar