Clinical Study
Different Impact of Pretransplant Anti-HLA Antibodies Detected by Luminex in Highly Sensitized Renal Transplanted Patients
Table 1
Demographic and clinical characteristics.
| | | Non-HS | HS | | HS Pre-Tx DSA | HS non-DSA | | | | | |
| | Donor | | | | | | | | Gender (% male) | 69% | 68% | 0.9 | 71% | 68% | 0.7 | | Age (years, mean ± SD) | 40 ± 15 | 39 ± 10 | 0.8 | 41 ± 12 | 40 ± 8 | 0.8 | | Recipient | | | | | | | | Gender (% male) | 64% | 62% | 0.8 | 61.5% | 30% | 0.1 | | Age (years, mean ± SD) | 50 ± 13 | 44 ± 10 | 0.03 | 43 ± 12 | 44 ± 16 | 0.9 | | HLA mismatch (median, IQR) | 4 (3–5) | 4 (3–5) | — | 4 (3–5) | 4 (3–5) | — | | Cold ischemia time (hours, mean ± SD) | 19 ± 5 | 18 ± 6 | 0.4 | 19 ± 5 | 17 ± 7 | 0.4 | | Delayed graft function (DGF)* | 62% | 65% | 0.7 | 67% | 63% | 0.5 | | Acute rejection (AR) | 33% | 57% | 0.03 | 77% | 30% | 0.03 | | Death censored 1 year allograft survival | 96% | 78% | 0.008 | 46% | 100% | 0.007 |
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DGF was defined as the need for dialysis during the first week after transplant.
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