Research Article
Moving toward Personalized Medicine in the Methadone Maintenance Treatment Program: A Pilot Study on the Evaluation of Treatment Responses in Taiwan
Table 4
Influence of ABCB1 polymorphism on methadone plasma concentrations in responders and nonresponders ()a.
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No available data on genotype for two subjects due to methodological problems. bR,S-Methadone, R-methadone, and S-methadone plasma concentrations were divided by the methadone dose (in milligrams per day) and by the patient weight (in kilograms). The unit of concentration is ng·kg/mL·mg. Then, the values were natural log transformed before analysis. All values are expressed as the mean and standard deviation (SD). *Statistical significance set at ; comparisons were performed by the ANOVA or Kruskal-Wallis test as appropriate. |