Hypoxia and Human Genome Stability: Downregulation of BRCA2 Expression in Breast Cancer Cell Lines
Figure 1
Role of hypoxia in cell proliferation. Cell proliferative activity was evaluated by BrdU incorporation assay. Data represent means of different culture experiments, each performed in triplicate and are presented as fold changes ± SD. Cell proliferative activity at time 0 was set to 1. MCF-7 (a), SKBr3 (b), and MDA-MB-231 (c) cell lines were cultured under normoxia or hypoxia for 24, 48, 72, and 96 hours.
