Acetylsalicylic Acid Reduces the Severity of Dextran Sodium Sulfate-Induced Colitis and Increases the Formation of Anti-Inflammatory Lipid Mediators

Figure 4

Assessment of lipid mediators. Shown are the arachidonic acid-derived lipoxin A₄ (a) and 15-epi-lipoxin A₄ (b) with 𝑛=3 for the control group, 𝑛=5 for both the DSS alone and the DSS plus ASA groups; ^ns𝑃=0.056 versus DSS (not significant); *𝑃=0.016 versus DSS. (c) The levels of 17-HDHA, with 𝑛=3 for the control group, 𝑛=5 for both the DSS alone and the DSS plus ASA groups; *𝑃=0.036 versus controls; **𝑃=0.008 versus DSS (b).

(a)

(b)

(c)