Cancer Morbidity in Rheumatoid Arthritis: Role of Estrogen Metabolites
Figure 1
The proposed mechanism for cancer morbidity in RA. 4-OHE2 (4-hydroxyestradiol), 2-OHE2 (2-hydroxyestradiol), (E2)-3,4-SQ (estradiol-3,4-semiquinone), (E2)-2,3-SQ (estradiol-2,3-semiquinone), (E2)-3,4-Q (estradiol-3,4-quinone), and (E2)-3,4-Q (estradiol-2,3-quinone).
