Solid Lipid Nanoparticles of Guggul Lipid as Drug Carrier for Transdermal Drug Delivery

Table 5

Pharmacokinetic parameters of the CEG and selected SLN formulations.

Formulation code	𝐶max (μg/mL)	𝑇max (h)	AUC (μg · hr/mL)
Commercial gel*	1.01±0.087	4	10.98±0.039
GMNG-3	5.11±1.07	6	92.8±1.012
SANG-3	3.98±1.42	6	68.74±1.49
GLNG-3	8.21±1.34	4	167.8±1.24

∗1 g gel formulation equivalent to 11.6 mg Diclofenac Diethylammonium for commercial gel (10 mg Diclofenac sodium).
^†100 mg gel formulation equivalent to 1 mg of Diclofenac sodium for GLNG-3,GMNG-3 and SANG-3.
All data expressed as mean ± S.D.; 𝑛=6; (𝑃≤0.05).