Research Article

Atrophy and Primary Somatosensory Cortical Reorganization after Unilateral Thoracic Spinal Cord Injury: A Longitudinal Functional Magnetic Resonance Imaging Study

Figure 3

Stimulation-induced posterior central gyrus activation was superimposed on the standard monkey brain atlas: for a representative subject, the enhanced BOLD signal intensity occurred before SCI (a) and 4 weeks (b), 8 weeks (c), and 12 weeks (d) after injury through innocuous temperature stimulation to the left limbs. Color bars indicate the T-scores. (a) Stimulation of the left lower limb (HL) and left upper limb (FL) activated different areas of the c-S1. The lower limb activation region shows a medial tendency, whereas the upper limb activation region shows a lateral tendency. ((b) and (c)) Changes in the positions of the S1 activation clusters after stimulation of the left upper limb. (d) Activation response of bilateral S1 at 12 weeks after the operation. The MNI coordinates of the slices are marked on the upper right corner of each diagram. L represents the left side. Central sulcus (cs), posterior central gyrus (pst), and intraparietal sulcus (ips) were identified using arrows.
753061.fig.003a
(a)
753061.fig.003b
(b)
753061.fig.003c
(c)
753061.fig.003d
(d)