Research Article

Exploring the Possible Role of Lysine Acetylation on Entamoeba histolytica Virulence: A Focus on the Dynamics of the Actin Cytoskeleton

Figure 2

Predicted binding site of acetylsalicylic acid in actin from Entamoeba histolytica. (a) Alignment of actin from Homo sapiens, Mus musculus, and Entamoeba histolytica. Identical amino acid residues are in blue and similar amino acid residues in green; in blue box are lysines and arginines, important residues for actin polymerization. (b) Amino acids from 37 to 64 are explicitly shown, and the actin around acetylsalicylic is depicted in blue and lys 62 in red.
757392.fig.002a
(a)
757392.fig.002b
(b)