The Multifaceted Aspects of Interstitial Lung Disease in Rheumatoid Arthritis

Figure 1

Possible pathogenetic mechanisms involved in the occurrence of interstitial lung disease in rheumatoid arthritis. ILD: interstitial lung disease, RF: rheumatoid factor, ACPA: anticyclic citrullinated peptide antibodies, VEGF: vascular endothelial growth factor, PDGF: platelet derived growth factor, PAD: peptidylarginine deiminase, and MTX: methotrexate, MMP: metalloproteinase.