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BioMed Research International
Volume 2013, Article ID 761823, 7 pages
Research Article

Increased Expression of CCN2 in the Red Flashing Light-Induced Myopia in Guinea Pigs

Department of Ophthalmology, Qilu Hospital, Shandong University, 107 Wenhua Xi Road, Jinan 250012, China

Received 6 April 2013; Revised 11 June 2013; Accepted 18 June 2013

Academic Editor: Youhua Liu

Copyright © 2013 Hong Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplemental Figure 1: The myopia animal model was constructed under different types of lights exposure. (A-C) The guinea pigs were exposed to the red flashing light (Group 1), white flashing light (Group 2) and natural white light (Group 3), respectively. (D) The guinea pigs were in tightly closed paper cartons and exposed to the flashing lights. From left to right, the carton was exposed to the white, yellow, green and red flashing light emitted by a PS-I programmable flash stimulator. (E) PS-I programmable flash stimulator was provided by Qilu Hospital, Shandong University. It has hundreds of diodes and circuit boards to produce various flashing lights, including white, yellow, green and red. The output power was adjusted appropriately to control the flashing light intensity at 8001ux and the radiation law was on for 2 seconds, dark 2 seconds.

  1. Supplementary Figure