Chromosome Instability and Oxidative Stress Markers in Patients with Ataxia Telangiectasia and Their Parents

Table 1

Frequency of chromosomal breaks observed in the different groups and treatments.

Frequency of chromosomal breaks
	Spontaneous	Bleomycin (6 μg/mL)	Radiation (3 Gy)
Patients
Frequency (min × max)	0.00–1.30	0.43–5.65	0.47–7.32
𝜒 frequencies/cell	0.18	1.63	2.10
𝑁^∘ cells (min × max)	30 × 50	30 × 50	30 × 50
Parents
Frequency (min × max)	0.00–0.13	0.00–1.27	0.23–0.93
𝜒 frequencies/cell	0.02	0.56	0.52
𝑁^∘ cells (min × max)	30 × 50	5 × 50	21 × 50
Control group
Frequency (min × max)	0.00–0.03	0.00–0.90	0.10–0.93
𝜒 frequencies/cell	0.01	0.47	0.56
𝑁^∘ cells (min × max)	30	4 × 30	13 × 30

𝜒: average frequency of chromosomal breaks per cell.