Research Article

Integrative Analysis of Methylome and Transcriptome Reveals the Importance of Unmethylated CpGs in Non-CpG Island Gene Activation

Figure 3

Interplay between pG and pG levels. (a) The median expressions of ten bins of pG were plotted separately for promoters with high (above median) and low (below median) methylation levels. The expression levels of the genes fell into three categories (high, middle, and low) schematically labeled by lines with different grayscale. Dividing the data into 20 bins gives the same results (Figure S19).
785731.fig.003a
(a)
785731.fig.003b
(b)