Late Adherent Human Bone Marrow Stromal Cells Form Bone and Restore the Hematopoietic Microenvironment In Vivo

Figure 8

Abundant bone formation in implant loaded with R-cells harvested at 12 weeks. The spaces between the bone trabeculae are filled with fibrovascular tissue (*), with dilated capillaries containing red blood cells. Despite the expressive bone formation with bone spreading over the histological section, there is no evidence of hematopoiesis. Residual vehicle (v) particles are seen as empty clear spaces. Four micra paraffin-embedded section stained by hematoxylin and eosin.