Chitosan Dermal Substitute and Chitosan Skin Substitute Contribute to Accelerated Full-Thickness Wound Healing in Irradiated Rats

Table 1

Physical observation of irradiated wounds after treatment with three biomaterials.

Assessment (Score)	Mean ± SEM
	Day 7	Day 14	Day 21
Infection-pus
Chitosan skin substitute	1.0±0	1.0±0	1.0±0
Chitosan dermal substitute	1.0±0	1.0±0	1.0±0
Duoderm CGF	1.0±0	1.0±0	1.0±0
Hematoma
Chitosan skin substitute	1.0±0	1.2±0.20	1.0±0
Chitosan dermal substitute	1.0±0	1.0±0	1.0±0
Duoderm CGF	1.0±0	1.0±0	1.0±0
Exudation
Chitosan skin substitute	3.0±0	3.0±0	3.0±0
Chitosan dermal substitute	3.0±0	3.0±0	3.0±0
Duoderm CGF	3.0±0	3.0±0	3.0±0
Odor
Chitosan skin substitute	3.0±0	3.0±0	3.0±0
Chitosan dermal substitute	3.0±0	3.0±0	3.0±0
Duoderm CGF	3.0±0	3.0±0	3.0±0
Flexibility
Chitosan skin substitute	2.4±0.24	2.4±0.24	3.0±0
Chitosan dermal substitute	2.2±0.20	2.4±0.24	2.4±0.24
Duoderm CGF	2.00±0	2.4±0.24	2.4±0.24
Adherence
Chitosan skin substitute	2.8±0.20	1.8±0.73	0.6±0.60
Chitosan dermal substitute	3.0±0	1.8±0.73	1.2±0.73
Duoderm CGF	2.4±0.24	2.4±0.60	1.8±0.73
Fluid accumulation
Chitosan skin substitute	3.0±0	3.0±0	3.0±0
Chitosan dermal substitute	3.0±0	3.0±0	3.0±0

The means were not significantly different between biomaterials (P > 0.05).