Research Article
Increased Toll-Like Receptor Signaling Pathways Characterize CD8+ Cells in Rapidly Progressive SIV Infection
Table 1
Comparison of expression levels of TLR signaling pathway and innate immunity genes in SIV-infected REG and RAP CD11b-depleted splenic cells. Expression levels were normalized using the average of 5 housekeeping genes and the ratio between RAP and REG animals’ dCT values was calculated issuing fold change. Shown are the genes whose expression is significantly changed between the groups, organized by functional categories of the TLRs and their adapter as well as interacting proteins, the downstream NFκB and JNK/p38 signaling pathways, as well as other related molecules (MAPK8IP3 is present in both the adapter/interacting and the JNK/p38 categories).
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