Antioxidant and Renoprotective Effects of Spirogyra neglecta (Hassall) Kützing Extract in Experimental Type 2 Diabetic Rats
Figure 1
Micrographs of conventional hematoxylin and eosin (H&E) staining of rat kidneys. A sagittal half of kidney from each experimental group was removed, fixed, embedded, cut, and stained by H&E (original magnification 200x for all panels). The data were repeated at least 3 times from separate sets of animals. The results were analyzed using bright-field microscopy. (a) Normal (ND), (b) normal treated with SNE (ND + SNE1.0), (c) T2DM (DM), (d) T2DM treated with vitamin C (DM + vitamin C), (e) T2DM treated with SNE at the dose of 0.25 g/kg BW (DM + SNE0.25), (f) T2DM treated with SNE at the dose of 0.5 g/kg BW (DM + SNE0.5), and (g and h) T2DM treated with SNE at the dose of 1.0 g/kg BW (DM + SNE1.0). Arrow “a” in all panels indicates the Bowman’s capsule space. Arrow labeled “b” indicates the proximal tubular epithelial cells and the lumen space. Abbreviation: glomerulus (G), Bowman’s capsule (Bm), macular densa (MD), proximal convoluted tubule (P), loop of Henle (LH), and distal convoluted tubules (D).
