Figure 2: Micrographs of periodic acid-Schiff (PAS) staining of rat kidneys. Light microscopy of sagittal half of kidney sections stained with PAS and counterstained with hematoxylin is shown (original magnification 200x for all panels). (a) Normal (ND), (b) T2DM treated with vitamin C (DM + vitamin C), (c) T2DM (DM), and (d) T2DM treated with SNE at the dose of 1.0 g/kg BW (DM + SNE1.0). The lesions of mesangial cells and glomerulus are indicated by arrow “a”; the proximal tubular epithelium and the lumen are indicated by arrow “b.” Abbreviation: glomerulus (G).