Effect of the Plasmid-DNA Vaccination on Macroscopic and Microscopic Damage Caused by the Experimental Chronic Trypanosoma cruzi Infection in the Canine Model
Figure 1
Splenomegaly and cardiomegaly during chronic stage of infection with Trypanosoma cruzi Ninoa strain in Beagle dogs. Splenomegaly and cardiomegaly were calculated by the mean spleen (a) and the mean heart (b) indices, respectively (±S.D.). Differences were considered as significant when (Kruskal-Wallis test among immunized/infected groups (including the mock-immunized/infected animals) and healthy non-infected animals was performed). imm = immunization.
