The Fold Variant BM4 Is Beneficial in a Therapeutic Bet v 1 Mouse Model

Figure 2

(a) Lung resistance and compliance of treated BALB/c mice were determined upon challenge with increasing levels of methacholine and are shown as deviation from baseline. (b) In BAL fluids IL-5 levels were determined by ELISA and lung infiltration by flow cytometry. (c) Cytokines secreted by re-stimulated splenocytes were quantified by FlowCytomix assay. Data are expressed as mean ± SD; statistics were calculated by 𝑡-test (^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001).

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