Modeling of the Renal Kinetics of the AT1 Receptor Specific PET Radioligand [11C]KR31173
Figure 7
Parameter correlations. (a) Correlation of distribution volume ratios DVR obtained with the convolution and deconvolution approaches is significant and confirms robustness of the parallel model. (b) Correlation between radioligand retention values from the time-activity curve () and from the impulse response function () shows that the noninvasive parameter () represents a good estimation of the invasive parameter (). (c) Correlation between and from convolution shows that radioligand retention obtained from time-activity curve noninvasively can be used for estimation of the invasive displaceable to nondisplaceable binding ratio. (d) Correlation between and from convolution shows that radioligand retention obtained from the impulse response function can also be used for estimation of the distribution volume ratios.
