High Expression and Purification of Amino-Terminal Fragment of Human Amyloid Precursor Protein in Pichia pastoris and Partial Analysis of Its Properties

Figure 7

Apoptosis of SHEP cells cultured 24 h in different concentrations of N-APP. (a): Control; (b)–(f): N-APP at different concentrations of 2.5, 5, 10, 20, and 40 μg/mL; for 24 h, apoptosis rates were 4.9%, 5.7%, 6.8%, 7.6%, and 7.3%.

(a) Control  

(b) 2.5 μg/mL

(c) 5.0 μg/mL

(d) 10 μg/mL

(e) 20 μg/mL

(f) 40 μg/mL