Listeria monocytogenes Meningitis in Adults: The Czech Republic Experience

Table 1

Demographic, clinical, and laboratory characteristics of adults with L. monocytogenes meningitis.

Variable	Patients (𝑛=31)
Age [years]^1	63 (26–80)
Elderly ≥65 years	15/31 (48)
Gender
Female	14/31 (45)
Male	17/31 (55)
Severe immunosuppression	9/31 (29)
Haematologic malignancy	5
Long-term corticosteroids	3
HIV infection	1
Other immunosuppressive comorbidity	10/31 (32)
Diabetes mellitus	5
Alcoholic liver disease	3
Autoimmune disease	2
Arterial hypertension^2	14/31 (45)
Time to treatment [hours]^1	48 (12–96)
≤48 hours	26/31 (84)
Symptoms at presentation^3
Fever	31/31 (100)
Altered mental status	27/31 (87)
Headache	19/23 (83)
Meningism	22/31 (71)
Vomiting	6/23 (26)
Seizures	4/26 (15)
Fever, meningism, altered mental status	21/31 (68)
GCS score^1	11 (3–15)
≤8	3/31 (10)
CSF findings^1
CSF leukocytes [1/μL]	680 (133–6,666)
CSF protein [g/L]	2.6 (0.6–7.6)
CSF/serum glucose ratio	0.28 (0.02–0.53)

Data are presented as no./total no. (%).
1Median range is used for continuous variables.
2Some patients had multiple comorbidities.
3Anamnestic data were not complete in eight patients.