Molecular Profiling Predicts the Existence of Two Functionally Distinct Classes of Ovarian Cancer Stroma

Table 4

The unique compatible ligands and receptors as potential interactions between the Cepi and the CS samples when multiple probes from Tables 3(a) and 3(b) are combined.

CS ligands	Compatible Cepi receptors	Cepi ligands	Compatible CS receptors
***CXCL12	***CXCR4	*CXCL12	***CXCR4
*FGF1	**FGFR2	*FGF1	**FGFR2
*FGF1	*FGFR3	*FGF1	*FGFR3
*FGF2	*FGFR3	**FGF9	*FGFR3
**FGF9	*FGFR3	**PDGFA	***PDGFRA
*HGF	*MET	**TGFB2	***TGFBR2
*PDGFA	***PDGFRA	**IL7	*IL7R
***TGFB2	***TGFBR2	**IL1B	*IL1R1
*IL7	**IL7R	**IL1B	*IL1R2
*WNT2	*FZD2	**WNT2	*FZD2
**WNT2B	*FZD10	**WNT2B	***FZD10
*WNT7A	**FZD7	**WNT7A	***FZD7

Significance of detection calls: ^∗𝑃≤0.05, ^∗∗𝑃≤0.005, and ^∗∗∗𝑃≤0.0005.