Rotenone Upregulates Alpha-Synuclein and Myocyte Enhancer Factor 2D Independently from Lysosomal Degradation Inhibition

Figure 1

Rotenone cytotoxicity in SH-SY5Y cells. Cell viability was assessed by MTT assay after 24-hour exposure to 25–800 nM rotenone. Values are expressed as % versus vehicle. 𝑁=4, repeated measures ANOVA test, followed by Dunnett’s post-test; ^∗𝑃<0.05; ^∗∗𝑃<0.01 versus vehicle.