Research Article
Abnormal Nerve Conduction Study Findings Indicating the Existence of Peripheral Neuropathy in Multiple Sclerosis and Neuromyelitis Optica
Table 1
Clinical characteristics associated with CNS demyelinating diseases of 9 patients with peripheral neuropathy.
| | Patient no. | Sex | MS or NMO | Age at onset | EDSS | Lesions determined by MRI (lesion number) | Number of relapses | OB | AQP-4 | DMT |
| | 1 | F | MS | 28 | 3.5 | Cerebrum and brainstem (>10), | 3 | + | − | − | | spinal cord (5) |
| | 2 | F | MS | 56 | 6.5 | Spinal cord (4) | Unidentified | + | − | − |
| | 3 | F | MS | 21 | 2.0 | Brainstem (1), | 2 | + | − | IFN | | spinal cord (5) |
| | 4 | M | MS | 62 | 7.5 | Spinal cord (4) | 4 | − | − | − |
| | 5 | F | MS | 38 | 6.0 | Cerebrum and brainstem (>10), | Countless | + | N.T. | − | | spinal cord (>10) |
| | 6 | F | MS | 33 | 3.0 | Cerebrum (>10), | 4 | N.T. | N.T. | − | | spinal cord (1) |
| | 7 | M | NMO | 48 | 9.0 | Brainstem (1), | 1 | N.T. | + | AZP | | spinal cord (1) |
| | 8 | F | NMO | 43 | 6.5 | Optic nerve (1), | 14 | N.T. | + | − | | cerebrum and brainstem (>10), | | spinal cord (1) |
| | 9 | F | NMO | 64 | 6.5 | Optic nerve (1), | 5 | − | + | PSL | | cerebrum and brainstem (10), | | spinal cord (2) |
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OB: Oligoclonal IgG bands
AQP-4: Antiaquaporin-4 autoantibody
N.T.: Not tested
DMT: Disease-modifying therapy
IFN: Interferon beta-1b
AZP: Azathioprine
PSL: Prednisolone
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