Integration of Data from Omic Studies with the Literature-Based Discovery towards Identification of Novel Treatments for Neovascularization in Diabetic Retinopathy

Table 3

The highest ranked GeneOntology terms, annotating top genes resulting from the meta-analysis of microarray studies performed in rat models of diabetic retinopathy.

GeneOntology term	P value*
Regulation of cell proliferation	2.5𝐸−4
Intracellular signaling cascade	7.4𝐸−3
Negativee regulation of macromolecule biosynthetic process	2.9𝐸−2
Response to wounding	3.0𝐸−2
Negative regulation of multicellular organismal process	3.9𝐸−2
Vasculature development	4.3𝐸−2

∗Significance values for enrichment are adjusted for multiple testing according to the Benjamini-Hochberg method.