Amelioration of Prallethrin-Induced Oxidative Stress and Hepatotoxicity in Rat by the Administration of Origanum majorana Essential Oil

Table 1

Histopathological changes in the liver of male rats exposed to prallethrin (Pral) and the protective effect of Origanum majorana essential oil (EO), based on scoring severity of injury.

Observation	Control	EO	Pral	Pral + EO
Inflammatory cells in the portal area	−	−	+++	+
Focal necrosis in the hepatic parenchyma	−	−	++	−
Diffuse kupffer proliferation	−	−	−	++

Normal (−), minimal (+), mild (++), moderate (+++).