7,8-Dihydroxyflavone Suppresses Oxidative Stress-Induced Base Modification in DNA via Induction of the Repair Enzyme 8-Oxoguanine DNA Glycosylase-1

<table>The proposed model of OGG1 induction by DHF treatment and its cytoprotective effect against cell death. DHF activates the OGG1 via the PI3K/Akt/Nrf2 signaling pathway and removes 8-oxoG in response to oxidative stress, resulting in prevention against cell death induced by oxidative damage.</table>

BioMed Research International

fig5

Figure 5

Figure 5: 7,8-Dihydroxyflavone Suppresses Oxidative Stress-Induced Base Modification in DNA via Induction of the Repair Enzyme 8-Oxoguanine DNA Glycosylase-1 

Figure 5 | 7,8-Dihydroxyflavone Suppresses Oxidative Stress-Induced Base Modification in DNA via Induction of the Repair Enzyme 8-Oxoguanine DNA Glycosylase-1 