[Retracted] MicroRNA-124 Regulates the Proliferation of Colorectal Cancer Cells by Targeting iASPP
Figure 2
miR-124 directly targets iASPP by binding to its 3′ UTR. (a) The predicted miR-124 binding site within the 3′ UTR of iASPP and the mutated version generated by site mutagenesis are shown. (b) Repression of wild-type iASPP 3′ UTR luciferase reporter gene activity by miR-124 (); miR-124 had no effect on the luciferase activity of the mutated iASPP 3′ UTR reporter vector compared to control HEK293 cells or cell transfected with scrambled miR lentivirus (without miR-124) (miR-SRC).
