miR-1279, miR-548j, miR-548m, and miR-548d-5p Binding Sites in CDSs of Paralogous and Orthologous PTPN12, MSH6, and ZEB1 Genes
Figure 1
Fragments of nucleotide and amino acid sequences, where miRNA binding sites are located. The variability of nucleotides in miR-1279 binding sites in mRNA of PTPN12 (a), MSH6 (c), and ZEB1 (e) orthologous genes and the variability of amino acids of PTPN12 (b), MSH6 (d), and ZEB1 (f) orthologous proteins; miR-1279 binding site encode TKEQYE (b), EGSSDE (d), and GEKPYE (f) oligopeptides; (g), the variability of nucleotides in miR-1279 binding sites of zinc-finger transcriptional factors family; (h), (j) and (l)—the variability of nucleotides in 548j, 548 m, and miR-548d-5p binding sites in mRNA of PTPN12, respectively; (i), (k), and (m), the variability of amino acids of PTPN12 orthologous proteins in regions with PRTRSC, EATDI, and STASAT oligopeptides, respectively.
