Clinical Study
Effectiveness of Naltrexone in the Prevention of Delayed Respiratory Arrest in Opioid-Naive Methadone-Intoxicated Patients
Table 1
Baseline characteristics of groups NLTX and Placebo.
| Characteristics |
Total | NLTX | Placebo | P value | | |
| Age | | | | | Mean ± SD | — | 26 ± 11 | 31 ± 12 | 0.03‡ | Sex | | | | | Male | 24 (44.4%) | 9 (33.3%) | 15 (55.6%) | 0.10* | Female | 30 (55.6%) | 18 (66.7%) | 12 (44.4%) | | Mode of toxicity | | | | | Suicidal | 45 (83.3%) | 24 (88.9%) | 21 (77.8%) | 0.48** | Accidental | 9 (16.7%) | 3 (11.1%) | 6 (22.2%) | | Formulation | | | | | Tablet | 20 (37.0%) | 10 (37.0%) | 10 (37.0%) | >0.99* | Syrup | 34 (63.0%) | 17 (63.0%) | 17 (63.0%) | | Ingested MTD doses (mg) | | | | | Mean ± SD | | | | 0.41‡ | Time since ingestion (hrs) | | | | | Mean ± SD | | | | 0.34‡ |
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Student’s t-test. ‡Mann-Whitney U test. *Chi-Square test. **Fisher’s exact test.
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